Work will start on Monday 27 July on the traffic lights at the junction of Sleaford Road, Brothertoft Road and Woodville Road.
Button-controlled crossings and tactile paving will be installed or upgraded on each approach to the junction, to make it easier for pedestrians and vulnerable road users to navigate.
The old traffic lights at the junction will also be replaced with new, ultra-low voltage equipment to drastically reduce the energy consumption and carbon footprint of the lights.
There will be road closures at the top of Woodville Road and Brothertoft Road whilst works are carried out. Local diversion routes and temporary crossings will be in place.
Cllr Richard Davies, executive member for highways at Lincolnshire County Council, said:
"We want our roads to be as safe as possible for all our roads users, so we're bringing the lights and crossings at this junction up to standard.
"It'll also mean that there's a safe way across the road, no matter which direction you approach the junction from.
"Thanks to residents in Boston for bearing with us whilst we make this a safer road."
Work is expected to be finished by 28 August.